Overview

SCIENTIFIC SCORE
Possibly Effective
Based on 3 Researches
7
USERS' SCORE
Good
Based on 163 Reviews
8.3
Supplement Facts
Serving Size: 2 Tablets
Amount Per Serving
%DV
Magnesium (from 2,000 mg magnesium lysinate glycinate chelate) (Albion®)
200 mg
48%

Top Medical Research Studies

7
CMT shows potential for pain relief
We investigated how choline magnesium trisalicylate (CMT) helps alleviate bone pain in patients with metastatic cancer. In a carefully designed study involving 26 participants, we compared CMT against a placebo in a crossover format, measuring pain relief at multiple intervals after dosing.

While we observed a significant reduction in pain just one hour post-treatment with CMT, other comparisons showed improvements that didn't reach statistical significance. This suggested that CMT might assist in managing bone pain, potentially complementing traditional opioids, but overall effectiveness is still under exploration.
Read More
7
Pamidronate therapy reduces bone pain
We evaluated the effects of pamidronate therapy on children with osteogenesis imperfecta type III. Over the course of treatment, we saw reductions in bone pain, alongside a significant decrease in fracture incidence.

The therapy positively impacted children's daily activities and their overall mobility. Importantly, the treatment was found to be safe, although some patients experienced mild side effects like low calcium levels and a fever. Overall, our findings suggest that bisphosphonate therapy is beneficial for management in these young patients.
Read More
7
Promising drug delivery for osteoporosis
We developed a novel drug delivery system combining denosumab and magnesium within metal-organic frameworks to target osteoarthritis. The framework showed good potential for loaded drug release, delivering about 72% of denosumab in just 8 hours.

Additionally, it released magnesium ions, which are beneficial for bone formation. Our cytotoxicity tests demonstrated that the system is biocompatible and encourages cell growth over time. While our findings are promising for pain relief linked to osteoporosis, further studies are needed to confirm effectiveness in real-world scenarios.
Read More

Most Useful Reviews

9
Improved quality of life
720 people found this helpful
I am smiling at my boss and love my mother-in-law! For over two years, I've experienced symptoms like anxiety, fatigue, and constant headaches, which I attributed to a lack of magnesium. Initially, I hesitated to take it, thinking it was just an “age-old” remedy. However, magnesium supplementation has transformed me from a tired individual into a calm person. My meteorological dependence and tearfulness have vanished, and the quality of life has improved dramatically. I recommend magnesium for overall wellness and vitality.
Read More
9
Relieved leg pain
326 people found this helpful
I highly recommend magnesium! I take it daily with my husband after breakfast and dinner. Within a week, the heaviness and pain in my legs disappeared. As someone with a sedentary job, I experienced calf pain, but this miracle remedy has truly changed things. My husband also noticed less leg pain and increased energy. We even bought it for our parents, who reported greater endurance and less drowsiness. Truly an amazing product!
Read More
9
Bone weakness solution
100 people found this helpful
Excellent! Magnesium has been a lifesaver for my bone weakness. It has improved muscle and heart functions and has strengthened my immune system. It’s a great find, even for preventative use.
Read More

Medical Researches

SCIENTIFIC SCORE
Possibly Effective
Based on 3 Researches
7
  • All Researches
7
Promising drug delivery for osteoporosis
We developed a novel drug delivery system combining denosumab and magnesium within metal-organic frameworks to target osteoarthritis. The framework showed good potential for loaded drug release, delivering about 72% of denosumab in just 8 hours.

Additionally, it released magnesium ions, which are beneficial for bone formation. Our cytotoxicity tests demonstrated that the system is biocompatible and encourages cell growth over time. While our findings are promising for pain relief linked to osteoporosis, further studies are needed to confirm effectiveness in real-world scenarios.
Read More
7
Pamidronate therapy reduces bone pain
We evaluated the effects of pamidronate therapy on children with osteogenesis imperfecta type III. Over the course of treatment, we saw reductions in bone pain, alongside a significant decrease in fracture incidence.

The therapy positively impacted children's daily activities and their overall mobility. Importantly, the treatment was found to be safe, although some patients experienced mild side effects like low calcium levels and a fever. Overall, our findings suggest that bisphosphonate therapy is beneficial for management in these young patients.
Read More
7
CMT shows potential for pain relief
We investigated how choline magnesium trisalicylate (CMT) helps alleviate bone pain in patients with metastatic cancer. In a carefully designed study involving 26 participants, we compared CMT against a placebo in a crossover format, measuring pain relief at multiple intervals after dosing.

While we observed a significant reduction in pain just one hour post-treatment with CMT, other comparisons showed improvements that didn't reach statistical significance. This suggested that CMT might assist in managing bone pain, potentially complementing traditional opioids, but overall effectiveness is still under exploration.
Read More

User Reviews

USERS' SCORE
Good
Based on 163 Reviews
8.3
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9
Improved quality of life
720 people found this helpful
I am smiling at my boss and love my mother-in-law! For over two years, I've experienced symptoms like anxiety, fatigue, and constant headaches, which I attributed to a lack of magnesium. Initially, I hesitated to take it, thinking it was just an “age-old” remedy. However, magnesium supplementation has transformed me from a tired individual into a calm person. My meteorological dependence and tearfulness have vanished, and the quality of life has improved dramatically. I recommend magnesium for overall wellness and vitality.
Read More
9
Relieved leg pain
326 people found this helpful
I highly recommend magnesium! I take it daily with my husband after breakfast and dinner. Within a week, the heaviness and pain in my legs disappeared. As someone with a sedentary job, I experienced calf pain, but this miracle remedy has truly changed things. My husband also noticed less leg pain and increased energy. We even bought it for our parents, who reported greater endurance and less drowsiness. Truly an amazing product!
Read More
9
Bone weakness solution
100 people found this helpful
Excellent! Magnesium has been a lifesaver for my bone weakness. It has improved muscle and heart functions and has strengthened my immune system. It’s a great find, even for preventative use.
Read More
9
Joint pain improved
97 people found this helpful
I'm thrilled with this magnesium and use it for myself and my parents. It greatly calms their nervous system and enhances sleep quality. My mum often suffers from joint pain, and magnesium has notably alleviated her discomfort. It's well-absorbed and doesn’t cause diarrhoea. We take two tablets at night.
Read More
9
Helps cramps and headaches
80 people found this helpful
My headaches have disappeared and my blood pressure has normalised thanks to this magnesium. It also aids in relieving leg cramps and pain during my menstrual period.
Read More

Frequently Asked Questions

9
Significant relief
41 people found this helpful
More than wonderful! I have suffered from severe neck and shoulder bone pain for years; medications prescribed by my doctor failed to provide relief. Since starting this treatment, I felt a significant difference within a week. I only wish I’d discovered this sooner!
9
Effective for knees
14 people found this helpful
Since I started using this product, my knee bone pain has significantly diminished. I strongly recommend this to anyone experiencing joint pain. I plan to order it again.
10
Knee pain relief
26 people found this helpful
If you have arthritis or rheumatism, you must try this supplement. After enduring five knee surgeries, my movement was severely limited. Just four days after taking this magnesium supplement, I experienced remarkable results—no more pain, better than any painkillers I've tried. It transformed my mobility and comfort.
10
Cured bone pain
8 people found this helpful
I had been experiencing pain in my waist and back for ages. Suspecting a magnesium deficiency, I started taking it and within a week, I was completely cured! It's now an essential part of my routine. I can't recommend it enough.
9
Improved quality of life
720 people found this helpful
I am smiling at my boss and love my mother-in-law! For over two years, I've experienced symptoms like anxiety, fatigue, and constant headaches, which I attributed to a lack of magnesium. Initially, I hesitated to take it, thinking it was just an “age-old” remedy. However, magnesium supplementation has transformed me from a tired individual into a calm person. My meteorological dependence and tearfulness have vanished, and the quality of life has improved dramatically. I recommend magnesium for overall wellness and vitality.
9
Relieved leg pain
326 people found this helpful
I highly recommend magnesium! I take it daily with my husband after breakfast and dinner. Within a week, the heaviness and pain in my legs disappeared. As someone with a sedentary job, I experienced calf pain, but this miracle remedy has truly changed things. My husband also noticed less leg pain and increased energy. We even bought it for our parents, who reported greater endurance and less drowsiness. Truly an amazing product!
8
Reduced nerve pain
61 people found this helpful
I initially purchased this for my grandmother, who suffers from debilitating carpal and cubital tunnel issues. She has experienced significant numbness and pain, requiring immobilisers at night. For over two years, she endured incessant nerve pain and insomnia. After taking this magnesium for 18 days, she started recommending it to family, as it has greatly improved her situation and helped with better absorption.
9
Super supplement
9 people found this helpful
I take magnesium not only as an essential supplement for women but also for sleep, calming, and muscle soreness. It truly is a super supplement. It complements Omega 3 for deep sleep and helps with period cramps alongside turmeric, reducing the need for painkillers. After trying a different brand, I returned to this one due to its effectiveness. It's one of the top five supplements one should have in their life.
9
Eliminated joint pain
11 people found this helpful
As a bariatric patient, I lost considerable weight, leading to muscle weakness, joint pain, and insomnia. After introducing magnesium and other vitamins into my regimen, my quality of life has tremendously improved. My sleep quality has enhanced markedly, and the pain has subsided. I recommend this product; while a downside is taking four tablets, I find them worthwhile.
9
Muscle strengthening aid
17 people found this helpful
Excellent! This product contains magnesium with boron, fantastic for muscle building and bone health. It helps with deep sleep and reduces anxiety. Just be sure to take enough calcium as well.
9
No more pains
46 people found this helpful
Excellent! Love it. Thanks to this, my monthly bone pain has vanished! I take 400 mg daily each week before my period. I previously relied on ibuprofen, which often didn’t help. I now enjoy my dinners and recommend this to anyone struggling with menstrual cramps.
7
CMT shows potential for pain relief
We investigated how choline magnesium trisalicylate (CMT) helps alleviate bone pain in patients with metastatic cancer. In a carefully designed study involving 26 participants, we compared CMT against a placebo in a crossover format, measuring pain relief at multiple intervals after dosing.

While we observed a significant reduction in pain just one hour post-treatment with CMT, other comparisons showed improvements that didn't reach statistical significance. This suggested that CMT might assist in managing bone pain, potentially complementing traditional opioids, but overall effectiveness is still under exploration.
7
Promising drug delivery for osteoporosis
We developed a novel drug delivery system combining denosumab and magnesium within metal-organic frameworks to target osteoarthritis. The framework showed good potential for loaded drug release, delivering about 72% of denosumab in just 8 hours.

Additionally, it released magnesium ions, which are beneficial for bone formation. Our cytotoxicity tests demonstrated that the system is biocompatible and encourages cell growth over time. While our findings are promising for pain relief linked to osteoporosis, further studies are needed to confirm effectiveness in real-world scenarios.
7
Pamidronate therapy reduces bone pain
We evaluated the effects of pamidronate therapy on children with osteogenesis imperfecta type III. Over the course of treatment, we saw reductions in bone pain, alongside a significant decrease in fracture incidence.

The therapy positively impacted children's daily activities and their overall mobility. Importantly, the treatment was found to be safe, although some patients experienced mild side effects like low calcium levels and a fever. Overall, our findings suggest that bisphosphonate therapy is beneficial for management in these young patients.

References

  1. Alsaikhan F, Mahmoud MZ, Suliman M. Synthesis and characterization of novel denosumab/magnesium-based metal organic frameworks nanocomposite prepared by ultrasonic route as drug delivery system for the treatment of osteoporosis. Front Bioeng Biotechnol. 2023;11:1153969. doi:10.3389/fbioe.2023.1153969
  2. Jakubowska-Pietkiewicz E, Chlebna-Sokół D. New trends in the treatment of osteogenesis imperfecta type III - own experience. Ortop Traumatol Rehabil. 2008;10:593.
  3. Johnson JR, Miller AJ. The efficacy of choline magnesium trisalicylate (CMT) in the management of metastatic bone pain: a pilot study. Palliat Med. 1994;8:129.
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